ASB6

The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011]

Description

Ankyrin repeat and SOCS box containing 6

Tissue specificity

Low tissue specificity

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

9 (129634604 - 129642169)

Ensembl ID

ENSG00000148331  (ver. 103.38)

Orthologs

Mouse Asb6: ENSMUSG00000039483

UniProt

Q9NWX5

neXtProt

NX_Q9NWX5

Human splice variants
Mouse splice variants

Protein structure