OPRK1

gene product
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
383 antibodies from 36 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Invitrogen Antibodies
9 antibodies
Novus Biologicals
16 antibodies
Biorbyt
16 antibodies
GeneTex
6 antibodies
Enzo Life Sciences
1 antibody
Abnova Corporation
6 antibodies
Affinity Biosciences
3 antibodies
Boster Biological Technology
2 antibodies
LifeSpan BioSciences, Inc.
60 antibodies
antibodies-online
125 antibodies
R&D Systems
10 antibodies
Acris Antibodies GmbH
7 antibodies
OriGene
9 antibodies
St John's Laboratory
6 antibodies
NovoPro Bioscience Inc.
3 antibodies
Antibodies.com
1 antibody
Aviva Systems Biology
6 antibodies
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
Creative Biolabs
9 antibodies
Creative Diagnostics
4 antibodies
Abgent
2 antibodies
Atlas Antibodies
1 antibody
Bioworld Technology, Inc
1 antibody
Neuromics
1 antibody
ProSci
3 antibodies
Abbiotec
1 antibody
MyBioSource
8 antibodies
GenWay
6 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
United States Biological
39 antibodies
Leading Biology
2 antibodies
RayBiotech, Inc.
2 antibodies
EMD Millipore
1 antibody
Sigma-Aldrich
1 antibody