PPFIBP2

This gene encodes a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. The encoded protein is a beta liprin and plays a role in axon guidance and neuronal synapse development by recruiting LAR protein-tyrosine phosphatases to the plasma membrane. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

Description

PPFIA binding protein 2

Tissue specificity

Low tissue specificity

Subcell location

Mitochondria

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)

Chromosome

11:p15.4 (7513298 - 7657127)

Ensembl ID

ENSG00000166387  (ver. 103.38)

Orthologs

Mouse Ppfibp2: ENSMUSG00000036528

UniProt

Q8ND30

neXtProt

NX_Q8ND30

Human splice variants
Mouse splice variants