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UBE2K
Ubiquitin conjugating enzyme E2 KHIP2, HYPG, UBC1
The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  11834-3-AP |
3 references | Polyclonal |
WB
EL
IHC
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| Novus Biologicals | NB300-840 |
2 references | Polyclonal |
WB
EL
IHC
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| antibodies-online | ABIN1882088 |
3 references | Polyclonal |
WB
ICC
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| NovoPro Bioscience Inc. | 122999 |
Polyclonal |
WB
EL
ICC
IHC
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| Abnova Corporation | PAB6301 |
1 references | Polyclonal |
WB
IHC
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