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Protein structure
NDE1
NudE neurodevelopment protein 1FLJ20101, NDE, nudE
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Top validated antibodies |
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| Proteintech Group |  10233-1-AP |
37 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 10233-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| Novus Biologicals | H00054820-M01 |
2 references | Monoclonal |
WB
EL
ICC
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| LSBio | LS-C346235 |
Polyclonal |
WB
ICC
IHC
|
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| antibodies-online | ABIN565777 |
2 references | Monoclonal |
WB
EL
ICC
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