NDE1
gene productFLJ20101, NDE, nudE
This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
Featured antibodies
![]() |
![]() |
0 references | Polyclonal |
IHC
![]() PA ![]() |
![]() |
![]() |
0 references | Polyclonal |
WB
![]() ICC ![]() IHC
![]() |
Antibodies
Filters






