BS8249

antibody from Bioworld Technology, Inc
Targeting: BCL2L14 BCL-G, BCLG
Provider product page for BS8249
Western blot
Immunohistochemistry

Antibody data

Product number
BS8249 - Provider product page
Provider
Bioworld Technology, Inc
Product name
BCL2L14 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human BCL2L14.
Description
Apoptosis is defined as a set of cascades which, when initiated, program the cell to undergo lethal changes such as membrane blebbing, mitochondrial breakdown and DNA fragmentation. Bcl-2 is one of many key regulators of apoptosis that are essential for proper development, tissue homeostasis and protection against foreign pathogens. Bcl-G, also known as BCL2L14 (BCL2-like 14) or BCLG, is a 327 amino acid cytoplasmic protein that belongs to the Bcl-2 family of apoptosis-regulating proteins. Bcl-G is expressed as three alternatively spliced transcripts designated short, medium and long. The short isoform is testis-specific and localizes to cytosolic organelles, while the long isoform is widely expressed and is distributed throughout the cytosol. Overexpression of Bcl-G induces apoptosis in cells, suggesting a possible role for Bcl-G in tumor suppression.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
BCL2L14 protein structure - BS8249 shown in red.