BS8041

antibody from Bioworld Technology, Inc
Targeting: RBL1 cp107, p107, PRB1
Provider product page for BS8041
Western blot

Antibody data

Product number
BS8041 - Provider product page
Provider
Bioworld Technology, Inc
Product name
RBL1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human RBL1.
Description
The human retinoblastoma gene product plays an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus encoded proteins. pRb and the structurally related p107 form complexes with E2F, a transcription factor originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Moreover, pRB and p107 share a high degree of structural homology in the adenovirus E1A binding domain (i.e. ¡ùpocket region¡ì) that is believed to play a primary role in the function of these proteins. A protein designated p130 shows a high degree of identity with pRb and p107 and also possesses a pocket region.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
RBL1 protein structure - BS8041 shown in red.