RBL1

gene product
cp107, p107, PRB1
The protein encoded by this gene is similar in sequence and possibly function to the product of the retinoblastoma 1 (RB1) gene. The RB1 gene product is a tumor suppressor protein that appears to be involved in cell cycle regulation, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle. Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein. In addition, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters. Due to the sequence and biochemical similarities with the RB1 protein, it is thought that the protein encoded by this gene may also be a tumor suppressor. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
384 antibodies from 32 providers.

Antibody properties

General

Applications

or Cancel
AntibodyRefsTypeWBELICCIPIHCFC
Atlas Antibodies
2 antibodies
Novus Biologicals
6 antibodies
Abnova Corporation
8 antibodies
antibodies-online
157 antibodies
Proteintech Group
1 antibody
NovoPro Bioscience Inc.
3 antibodies
GeneTex
4 antibodies
Biorbyt
22 antibodies
LifeSpan BioSciences, Inc.
54 antibodies
Invitrogen Antibodies
5 antibodies
Aviva Systems Biology
5 antibodies
OriGene
8 antibodies
Acris Antibodies GmbH
3 antibodies
Abgent
2 antibodies
Boster Biological Technology
1 antibody
NSJ Bioreagents
1 antibody
Affinity Biosciences
1 antibody
Cell Signaling Technology, Inc
1 antibody
Bioworld Technology, Inc
2 antibodies
MyBioSource
6 antibodies
Bethyl Laboratories
1 antibody
United States Biological
38 antibodies
Abbkine Scientific Co.Ltd.
2 antibodies
St John's Laboratory
2 antibodies
Creative Biolabs
3 antibodies
Creative Diagnostics
2 antibodies
Abbexa
3 antibodies
Sigma-Aldrich
2 antibodies
Exalpha Biologicals, Inc.
1 antibody
GenWay
1 antibody
ProSci
1 antibody