ITGA9

This gene encodes an alpha integrin. Integrins are heterodimeric integral membrane glycoproteins composed of an alpha chain and a beta chain that mediate cell-cell and cell-matrix adhesion. The protein encoded by this gene, when bound to the beta 1 chain, forms an integrin that is a receptor for VCAM1, cytotactin and osteopontin. Expression of this gene has been found to be upregulated in small cell lung cancers. [provided by RefSeq, Jul 2008]

Description

Integrin subunit alpha 9

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Vesicles, Plasma membrane, Cell Junctions

Predicted location

Intracellular, Membrane

Protein family

Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

3:p22.2 (37452115 - 37823507)

Ensembl ID

ENSG00000144668  (ver. 103.38)

Orthologs

Mouse Itga9: ENSMUSG00000039115

UniProt

Q13797

neXtProt

NX_Q13797

Human splice variants
Mouse splice variants