Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 339013 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#339013, RRID:AB_2562596
- Product name
- PE/Cy7 anti-human CD122 (IL-2Rß)
- Antibody type
- Monoclonal
- Antigen
- TL-Mor cell line
- Description
- CD122 is a 70-75 kD type I transmembrane glycoprotein and member of the Ig superfamily. It is IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. CD122 is constitutively expressed by NK cells and at lower levels by a subset of T cells. Its expression is upregulated upon activation. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antibody clone number
- TU27
- Vial size
- 25 tests
- Storage
- 2°C-8°C
- Handling
- Ambient RT
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Supportive validation
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- BioLegend (provider)
- Main image
- Experimental details
- Human peripheral blood lymphocytes were stained with CD56 APC and CD122 (clone TU27) PE/Cy7 (top) or mouse IgG1, κ PE/Cy7 isotype control (bottom).
- Conjugate
- Near infrared dye