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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [6]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB224P - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal IL-2 R beta Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from ascites. Detects human IL-2 R beta in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rh gamma c, rhIL-4 R, or rhIL-6 R is observed.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Submitted references Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration.
Identification of human NK17/NK1 cells.
A novel immunomodulatory mechanism of ribavirin in suppressing natural killer cell function.
Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patients.
Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patients.
Histone deacetylase inhibitors suppress natural killer cell cytolytic activity.
Arneja A, Johnson H, Gabrovsek L, Lauffenburger DA, White FM
Journal of immunology (Baltimore, Md. : 1950) 2014 Jan 1;192(1):123-35
Journal of immunology (Baltimore, Md. : 1950) 2014 Jan 1;192(1):123-35
Identification of human NK17/NK1 cells.
Pandya AD, Al-Jaderi Z, Høglund RA, Holmøy T, Harbo HF, Norgauer J, Maghazachi AA
PloS one 2011;6(10):e26780
PloS one 2011;6(10):e26780
A novel immunomodulatory mechanism of ribavirin in suppressing natural killer cell function.
Ogbomo H, Michaelis M, Altenbrandt B, Doerr HW, Cinatl J Jr
Biochemical pharmacology 2010 Jan 15;79(2):188-97
Biochemical pharmacology 2010 Jan 15;79(2):188-97
Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patients.
Zheng CF, Jones GJ, Shi M, Wiseman JC, Marr KJ, Berenger BM, Huston SM, Gill MJ, Krensky AM, Kubes P, Mody CH
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7221-9
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7221-9
Late expression of granulysin by microbicidal CD4+ T cells requires PI3K- and STAT5-dependent expression of IL-2Rbeta that is defective in HIV-infected patients.
Zheng CF, Jones GJ, Shi M, Wiseman JC, Marr KJ, Berenger BM, Huston SM, Gill MJ, Krensky AM, Kubes P, Mody CH
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7221-9
Journal of immunology (Baltimore, Md. : 1950) 2008 Jun 1;180(11):7221-9
Histone deacetylase inhibitors suppress natural killer cell cytolytic activity.
Ogbomo H, Michaelis M, Kreuter J, Doerr HW, Cinatl J Jr
FEBS letters 2007 Apr 3;581(7):1317-22
FEBS letters 2007 Apr 3;581(7):1317-22
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Supportive validation
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- Novus Biologicals (provider)
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- Experimental details
- Detection of IL-2 R beta in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human IL-2 R beta PE-conjugated Monoclonal Antibody (Catalog # FAB224P) and Mouse Anti-Human NCAM-1/CD56 APC-conjugated Monoclonal Antibody (Catalog # FAB2408A). Quadrant markers were set based on control antibody staining (Catalog # IC002P). View our protocol for Staining Membrane-associated Proteins.
