CABT-BL7790

antibody from Creative Diagnostics

Targeting: IL2RB CD122, IL15RB

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL7790

Provider

Creative Diagnostics

Product name

Anti-IL2RB Monoclonal antibody, clone 6I5 [Biotin]

Antibody type

Monoclonal

Description

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.

Reactivity

Mouse

Host

Rat

Conjugate

Biotin

Isotype

IgG