ABIN863200

antibody from antibodies-online

Targeting: SLC12A1 NKCC2

Western blot (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN863200

Provider

antibodies-online

Product name

anti-Solute Carrier Family 12 (Sodium/potassium/chloride Transporters), Member 1 (SLC12A1) antibody

Antibody type

Polyclonal

Antigen

AA109 to 129 of the rat sequence

Reactivity

Human, Mouse, Rat

Host

Rabbit

Vial size

100 µl

Storage

Store at -20°C. Shipping Temperature: Blue Ice or 4°C

References

Submitted references

Regulation of the Na(+)-K(+)-2Cl(-) cotransporter by cGMP/cGMP-dependent protein kinase I after furosemide administration.

Limmer F, Schinner E, Castrop H, Vitzthum H, Hofmann F, Schlossmann J
The FEBS journal 2015 Oct;282(19):3786-98

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Inhibition of Mitochondrial Complex-1 Prevents the Downregulation of NKCC2 and ENaCα in Obstructive Kidney Disease.

Zhang Y, Sun Y, Ding G, Huang S, Zhang A, Jia Z
Scientific reports 2015 Jul 24;5:12480

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Novel mechanisms of Na+ retention in obesity: phosphorylation of NKCC2 and regulation of SPAK/OSR1 by AMPK.

Davies M, Fraser SA, Galic S, Choy SW, Katerelos M, Gleich K, Kemp BE, Mount PF, Power DA
American journal of physiology. Renal physiology 2014 Jul 1;307(1):F96-F106

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cAMP stimulates apical exocytosis of the renal Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in the thick ascending limb: role of protein kinase A.

Caceres PS, Ares GR, Ortiz PA
The Journal of biological chemistry 2009 Sep 11;284(37):24965-71

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Expression of NKCC2 in the rat gastrointestinal tract.

Xue H, Liu S, Ji T, Ren W, Zhang XH, Zheng LF, Wood JD, Zhu JX
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 2009 Oct;21(10):1068-e89

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB