SLC12A1

gene product
NKCC2
This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven. [provided by RefSeq, May 2010]
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243 antibodies from 34 providers.

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Proteintech Group
1 antibody
Novus Biologicals
5 antibodies
NovoPro Bioscience Inc.
3 antibodies
GeneTex
2 antibodies
Boster Biological Technology
2 antibodies
antibodies-online
72 antibodies
LifeSpan BioSciences, Inc.
59 antibodies
OriGene
4 antibodies
NSJ Bioreagents
2 antibodies
Biorbyt
12 antibodies
Atlas Antibodies
2 antibodies
Aviva Systems Biology
1 antibody
Invitrogen Antibodies
6 antibodies
FabGennix
3 antibodies
Cell Signaling Technology, Inc
2 antibodies
Bioworld Technology, Inc
1 antibody
ProSci
1 antibody
Everest Biotech
1 antibody
Creative Biolabs
11 antibodies
Acris Antibodies GmbH
3 antibodies
Abnova Corporation
2 antibodies
Abbexa
2 antibodies
Abgent
3 antibodies
Creative Diagnostics
2 antibodies
Affinity Biosciences
1 antibody
St John's Laboratory
1 antibody
United States Biological
27 antibodies
Sigma-Aldrich
3 antibodies
MyBioSource
2 antibodies
EMD Millipore
2 antibodies
RabMAbs
1 antibody
Leading Biology
2 antibodies
GenWay
1 antibody
RayBiotech, Inc.
1 antibody