Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
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- Product number
- AF686 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IL-6 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects porcine IL-6 in ELISAs and Western blots. In sandwich ELISAs, less than 0.3% cross-reactivity with recombinant human IL-6, recombinant mouse IL-6, and recombinant rat IL-6 is observed.
- Reactivity
- Porcine
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references TRAF6 is a novel NS3-interacting protein that inhibits classical swine fever virus replication.
Protective Role of Passively Transferred Maternal Cytokines against Bordetella pertussis Infection in Newborn Piglets.
Differential Effects of Escherichia coli Nissle and Lactobacillus rhamnosus Strain GG on Human Rotavirus Binding, Infection, and B Cell Immunity.
Atorvastatin treatment improves survival and effects of implanted mesenchymal stem cells in post-infarct swine hearts.
In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid.
In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid.
The effect of activated protein C on plasma cytokine levels in a porcine model of acute endotoxemia.
Cytokine responses in gnotobiotic pigs after infection with virulent or attenuated human rotavirus.
Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model.
Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model.
Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model.
Lv H, Dong W, Cao Z, Li X, Wang J, Qian G, Lv Q, Wang C, Guo K, Zhang Y
Scientific reports 2017 Jul 27;7(1):6737
Scientific reports 2017 Jul 27;7(1):6737
Protective Role of Passively Transferred Maternal Cytokines against Bordetella pertussis Infection in Newborn Piglets.
Elahi S, Thompson DR, Van Kessel J, Babiuk LA, Gerdts V
Infection and immunity 2017 Apr;85(4)
Infection and immunity 2017 Apr;85(4)
Differential Effects of Escherichia coli Nissle and Lactobacillus rhamnosus Strain GG on Human Rotavirus Binding, Infection, and B Cell Immunity.
Kandasamy S, Vlasova AN, Fischer D, Kumar A, Chattha KS, Rauf A, Shao L, Langel SN, Rajashekara G, Saif LJ
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1780-9
Journal of immunology (Baltimore, Md. : 1950) 2016 Feb 15;196(4):1780-9
Atorvastatin treatment improves survival and effects of implanted mesenchymal stem cells in post-infarct swine hearts.
Yang YJ, Qian HY, Huang J, Geng YJ, Gao RL, Dou KF, Yang GS, Li JJ, Shen R, He ZX, Lu MJ, Zhao SH
European heart journal 2008 Jun;29(12):1578-90
European heart journal 2008 Jun;29(12):1578-90
In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid.
Saurer L, McCullough KC, Summerfield A
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):3504-14
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):3504-14
In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid.
Saurer L, McCullough KC, Summerfield A
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):3504-14
Journal of immunology (Baltimore, Md. : 1950) 2007 Sep 15;179(6):3504-14
The effect of activated protein C on plasma cytokine levels in a porcine model of acute endotoxemia.
Nielsen JS, Larsson A, Rix T, Nyboe R, Gjedsted J, Krog J, Ledet T, Tønnesen E
Intensive care medicine 2007 Jun;33(6):1085-93
Intensive care medicine 2007 Jun;33(6):1085-93
Cytokine responses in gnotobiotic pigs after infection with virulent or attenuated human rotavirus.
Azevedo MS, Yuan L, Pouly S, Gonzales AM, Jeong KI, Nguyen TV, Saif LJ
Journal of virology 2006 Jan;80(1):372-82
Journal of virology 2006 Jan;80(1):372-82
Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model.
Carter AJ, Aggarwal M, Kopia GA, Tio F, Tsao PS, Kolata R, Yeung AC, Llanos G, Dooley J, Falotico R
Cardiovascular research 2004 Sep 1;63(4):617-24
Cardiovascular research 2004 Sep 1;63(4):617-24
Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model.
Brix-Christensen V, Andersen SK, Andersen R, Mengel A, Dyhr T, Andersen NT, Larsson A, Schmitz O, Ørskov H, Tønnesen E
Anesthesiology 2004 Apr;100(4):861-70
Anesthesiology 2004 Apr;100(4):861-70
Acute hyperinsulinemia restrains endotoxin-induced systemic inflammatory response: an experimental study in a porcine model.
Brix-Christensen V, Andersen SK, Andersen R, Mengel A, Dyhr T, Andersen NT, Larsson A, Schmitz O, Ørskov H, Tønnesen E
Anesthesiology 2004 Apr;100(4):861-70
Anesthesiology 2004 Apr;100(4):861-70
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Cell Proliferation Induced by IL-6 and Neutralization by Porcine IL-6 Antibody. Recombinant Porcine IL-6 (Catalog # 686-PI) stimulates proliferation in the T1165.85.2.1 mouse plasmacytoma cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Porcine IL-6 (12.5 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Porcine IL-6 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF686). The ND50 is typically 0.15-0.6 µg/mL.