IL6

gene product
BSF2, HGF, HSF, IFNB2, IL-6
This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011]
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Antibodies

 

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Antibodypedia Validation Initiative

Validation method

Application

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Host

Reactivity

Antibody type

Conjugate

  or   Clear
Validated by best practice
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
1952 antibodies from 42 providers.

Antibody properties

Applications

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
149 antibodies
Abgent
8 antibodies
GeneTex
44 antibodies
R&D Systems
64 antibodies
antibodies-online
432 antibodies
OriGene
67 antibodies
LifeSpan BioSciences, Inc.
327 antibodies