Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- ABIN358951 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Interleukin 1 Receptor-Like 2 (IL1RL2) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal(E487) region of human IL1R.
- Description
- Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- C-Term
- Vial size
- 0.4 mL
- Concentration
- 0.25 mg/mL
- Storage
- Store the antibody undiluted at 2-8°C for one month or (in aliquots) at-20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Two novel IL-1 family members, IL-1 delta and IL-1 epsilon, function as an antagonist and agonist of NF-kappa B activation through the orphan IL-1 receptor-related protein 2.
Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q.
Purification and characterization of the human interleukin-18 receptor.
Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL 1R-rp2).
Debets R, Timans JC, Homey B, Zurawski S, Sana TR, Lo S, Wagner J, Edwards G, Clifford T, Menon S, Bazan JF, Kastelein RA
Journal of immunology (Baltimore, Md. : 1950) 2001 Aug 1;167(3):1440-6
Journal of immunology (Baltimore, Md. : 1950) 2001 Aug 1;167(3):1440-6
Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q.
Dale M, Nicklin MJ
Genomics 1999 Apr 1;57(1):177-9
Genomics 1999 Apr 1;57(1):177-9
Purification and characterization of the human interleukin-18 receptor.
Torigoe K, Ushio S, Okura T, Kobayashi S, Taniai M, Kunikata T, Murakami T, Sanou O, Kojima H, Fujii M, Ohta T, Ikeda M, Ikegami H, Kurimoto M
The Journal of biological chemistry 1997 Oct 10;272(41):25737-42
The Journal of biological chemistry 1997 Oct 10;272(41):25737-42
Cloning of a cDNA encoding a novel interleukin-1 receptor related protein (IL 1R-rp2).
Lovenberg TW, Crowe PD, Liu C, Chalmers DT, Liu XJ, Liaw C, Clevenger W, Oltersdorf T, De Souza EB, Maki RA
Journal of neuroimmunology 1996 Nov;70(2):113-22
Journal of neuroimmunology 1996 Nov;70(2):113-22
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of anti-IL1R in HL60 cell line lysates (35ug/lane). IL1R (arrow) was detected using the purified Pab (1:60 dilution).
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with IL1R antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.