Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations [0]
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- Product number
- MAB2061 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human IL-6 Monoclonal Antibody (Clone 1936)
- Antibody type
- Monoclonal
- Antigen
- E. coli-derived recombinant human IL-6, Val30-Met212
- Description
- Protein A or G purified from ascites
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
P05231
- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Contribution of three-dimensional architecture and tumor-associated fibroblasts to hepcidin regulation in breast cancer.
Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma.
Oral fibroblasts modulate the macrophage response to bacterial challenge.
Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses.
NOTCH1 mediates a switch between two distinct secretomes during senescence.
IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts.
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor.
Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam.
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation.
Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation.
Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma.
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment.
Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis.
Blanchette-Farra N, Kita D, Konstorum A, Tesfay L, Lemler D, Hegde P, Claffey KP, Torti FM, Torti SV
Oncogene 2018 Jul;37(29):4013-4032
Oncogene 2018 Jul;37(29):4013-4032
Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma.
Brencicova E, Jagger AL, Evans HG, Georgouli M, Laios A, Attard Montalto S, Mehra G, Spencer J, Ahmed AA, Raju-Kankipati S, Taams LS, Diebold SS
PloS one 2017;12(4):e0175712
PloS one 2017;12(4):e0175712
Oral fibroblasts modulate the macrophage response to bacterial challenge.
Tzach-Nahman R, Nashef R, Fleissig O, Palmon A, Shapira L, Wilensky A, Nussbaum G
Scientific reports 2017 Sep 14;7(1):11516
Scientific reports 2017 Sep 14;7(1):11516
Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses.
Cheng WC, van Asten SD, Burns LA, Evans HG, Walter GJ, Hashim A, Hughes FJ, Taams LS
European journal of immunology 2016 Sep;46(9):2211-21
European journal of immunology 2016 Sep;46(9):2211-21
NOTCH1 mediates a switch between two distinct secretomes during senescence.
Hoare M, Ito Y, Kang TW, Weekes MP, Matheson NJ, Patten DA, Shetty S, Parry AJ, Menon S, Salama R, Antrobus R, Tomimatsu K, Howat W, Lehner PJ, Zender L, Narita M
Nature cell biology 2016 Sep;18(9):979-92
Nature cell biology 2016 Sep;18(9):979-92
IL-1α released from damaged epithelial cells is sufficient and essential to trigger inflammatory responses in human lung fibroblasts.
Suwara MI, Green NJ, Borthwick LA, Mann J, Mayer-Barber KD, Barron L, Corris PA, Farrow SN, Wynn TA, Fisher AJ, Mann DA
Mucosal immunology 2014 May;7(3):684-93
Mucosal immunology 2014 May;7(3):684-93
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor.
Becker TM, Boyd SC, Mijatov B, Gowrishankar K, Snoyman S, Pupo GM, Scolyer RA, Mann GJ, Kefford RF, Zhang XD, Rizos H
Oncogene 2014 Feb 27;33(9):1158-66
Oncogene 2014 Feb 27;33(9):1158-66
Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam.
Nakajima N, Van Tin N, Sato Y, Thach HN, Katano H, Diep PH, Kumasaka T, Thuy NT, Hasegawa H, San LT, Kawachi S, Liem NT, Suzuki K, Sata T
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 Mar;26(3):357-69
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2013 Mar;26(3):357-69
IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation.
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, Hoppe E, Barré B, Audran M, Bouvard B, Saint-André JP, Jeannin P
PLoS biology 2012;10(9):e1001395
PLoS biology 2012;10(9):e1001395
Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation.
Steinbicker AU, Sachidanandan C, Vonner AJ, Yusuf RZ, Deng DY, Lai CS, Rauwerdink KM, Winn JC, Saez B, Cook CM, Szekely BA, Roy CN, Seehra JS, Cuny GD, Scadden DT, Peterson RT, Bloch KD, Yu PB
Blood 2011 May 5;117(18):4915-23
Blood 2011 May 5;117(18):4915-23
Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma.
Maneechotesuwan K, Wamanuttajinda V, Kasetsinsombat K, Huabprasert S, Yaikwawong M, Barnes PJ, Wongkajornsilp A
The Journal of allergy and clinical immunology 2009 Jan;123(1):239-48
The Journal of allergy and clinical immunology 2009 Jan;123(1):239-48
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.
Rodier F, Coppé JP, Patil CK, Hoeijmakers WA, Muñoz DP, Raza SR, Freund A, Campeau E, Davalos AR, Campisi J
Nature cell biology 2009 Aug;11(8):973-9
Nature cell biology 2009 Aug;11(8):973-9
Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment.
Chong DY, Boehlke CS, Zheng QD, Zhang L, Han Y, Zacks DN
Investigative ophthalmology & visual science 2008 Jul;49(7):3193-200
Investigative ophthalmology & visual science 2008 Jul;49(7):3193-200
Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis.
Ren Y, Lin CL, Li Z, Chen XY, Huang X, Lui V, Nicholls J, Lan HY, Tam PK
Histopathology 2005 Jun;46(6):659-67
Histopathology 2005 Jun;46(6):659-67
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