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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 11603-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11603-1-AP, RRID:AB_2073774
- Product name
- CCT5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CCT5 antibody (Cat. #11603-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRiC/CCT chaperonin is required for the folding and inhibitory effect of WDTC1 on adipogenesis.
Novel biomarkers to predict treatment response and prognosis in locally advanced rectal cancer undergoing neoadjuvant chemoradiotherapy.
Chaperonin-Containing TCP1 Subunit 5 Protects Against the Effect of Mer Receptor Tyrosine Kinase Knockdown in Retinal Pigment Epithelial Cells by Interacting With Filamentous Actin and Activating the LIM-Kinase 1/Cofilin Pathway.
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.
CEP55 promotes cilia disassembly through stabilizing Aurora A kinase.
CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion.
Avian Chaperonin Containing TCP1 Subunit 5 Supports Influenza A Virus Replication by Interacting With Viral Nucleoprotein, PB1, and PB2 Proteins.
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.
Antigenic group II chaperonin in Methanobrevibacter oralis may cross-react with human chaperonin CCT.
Tang WS, Cen X, Yao SS, Yin ST, Weng L, Zhao TJ, Wang X
Frontiers in cell and developmental biology 2023;11:1225628
Frontiers in cell and developmental biology 2023;11:1225628
Novel biomarkers to predict treatment response and prognosis in locally advanced rectal cancer undergoing neoadjuvant chemoradiotherapy.
Guan B, Xu M, Zheng R, Guan G, Xu B
BMC cancer 2023 Nov 12;23(1):1099
BMC cancer 2023 Nov 12;23(1):1099
Chaperonin-Containing TCP1 Subunit 5 Protects Against the Effect of Mer Receptor Tyrosine Kinase Knockdown in Retinal Pigment Epithelial Cells by Interacting With Filamentous Actin and Activating the LIM-Kinase 1/Cofilin Pathway.
Feng L, Li H, Du Y, Zhang T, Zhu Y, Li Z, Zhao L, Wang X, Wang G, Zhou L, Jiang Z, Liu Z, Ou Z, Wen Y, Zhuo Y
Frontiers in medicine 2022;9:861371
Frontiers in medicine 2022;9:861371
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates.
Ma X, Lu C, Chen Y, Li S, Ma N, Tao X, Li Y, Wang J, Zhou M, Yan YB, Li P, Heydari K, Deng H, Zhang M, Yi C, Ge L
Cell 2022 Apr 14;185(8):1325-1345.e22
Cell 2022 Apr 14;185(8):1325-1345.e22
CEP55 promotes cilia disassembly through stabilizing Aurora A kinase.
Zhang YC, Bai YF, Yuan JF, Shen XL, Xu YL, Jian XX, Li S, Song ZQ, Hu HB, Li PY, Tu HQ, Han QY, Wang N, Li AL, Zhang XM, Wu M, Zhou T, Li HY
The Journal of cell biology 2021 Feb 1;220(2)
The Journal of cell biology 2021 Feb 1;220(2)
CCT5 interacts with cyclin D1 promoting lung adenocarcinoma cell migration and invasion.
Meng Y, Yang L, Wei X, Luo H, Hu Y, Tao X, He J, Zheng X, Xu Q, Luo K, Yu G, Luo Q
Biochemical and biophysical research communications 2021 Aug 27;567:222-229
Biochemical and biophysical research communications 2021 Aug 27;567:222-229
Avian Chaperonin Containing TCP1 Subunit 5 Supports Influenza A Virus Replication by Interacting With Viral Nucleoprotein, PB1, and PB2 Proteins.
Zhang X, Lin X, Qin C, Huang K, Sun X, Zhao L, Jin M
Frontiers in microbiology 2020;11:538355
Frontiers in microbiology 2020;11:538355
DYX1C1 is required for axonemal dynein assembly and ciliary motility.
Tarkar A, Loges NT, Slagle CE, Francis R, Dougherty GW, Tamayo JV, Shook B, Cantino M, Schwartz D, Jahnke C, Olbrich H, Werner C, Raidt J, Pennekamp P, Abouhamed M, Hjeij R, Köhler G, Griese M, Li Y, Lemke K, Klena N, Liu X, Gabriel G, Tobita K, Jaspers M, Morgan LC, Shapiro AJ, Letteboer SJ, Mans DA, Carson JL, Leigh MW, Wolf WE, Chen S, Lucas JS, Onoufriadis A, Plagnol V, Schmidts M, Boldt K, UK10K, Roepman R, Zariwala MA, Lo CW, Mitchison HM, Knowles MR, Burdine RD, Loturco JJ, Omran H
Nature genetics 2013 Sep;45(9):995-1003
Nature genetics 2013 Sep;45(9):995-1003
BBS6, BBS10, and BBS12 form a complex with CCT/TRiC family chaperonins and mediate BBSome assembly.
Seo S, Baye LM, Schulz NP, Beck JS, Zhang Q, Slusarski DC, Sheffield VC
Proceedings of the National Academy of Sciences of the United States of America 2010 Jan 26;107(4):1488-93
Proceedings of the National Academy of Sciences of the United States of America 2010 Jan 26;107(4):1488-93
Antigenic group II chaperonin in Methanobrevibacter oralis may cross-react with human chaperonin CCT.
Yamabe K, Maeda H, Kokeguchi S, Soga Y, Meguro M, Naruishi K, Asakawa S, Takashiba S
Molecular oral microbiology 2010 Apr;25(2):112-22
Molecular oral microbiology 2010 Apr;25(2):112-22
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11603-1-AP(CCT5 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using CCT5 antibody 11603-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11603-1-AP(CCT5 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
