GPRC5B

This gene encodes a member of the type 3 G protein-coupled receptor family. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The encoded protein may modulate insulin secretion and increased protein expression is associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Description

G protein-coupled receptor class C group 5 member B

Tissue specificity

Tissue enriched (brain)

Subcell location

Nucleoplasm, Nucleoli, Vesicles

Predicted location

Intracellular, Membrane

Protein family

G-protein coupled receptors
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16:p12.3 (19856691 - 19886167)

Ensembl ID

ENSG00000167191  (ver. 103.38)

Orthologs

Mouse Gprc5b: ENSMUSG00000008734

UniProt

Q9NZH0

neXtProt

NX_Q9NZH0

Human splice variants
Mouse splice variants