ANGPTL1

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. [provided by RefSeq, Jul 2008]

Description

Angiopoietin like 1

Tissue specificity

Tissue enhanced (placenta)

Predicted location

Secreted to blood

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

1 (178849535 - 178871077)

Ensembl ID

ENSG00000116194  (ver. 103.38)

Orthologs

Mouse Angptl1: ENSMUSG00000033544

UniProt

O95841

neXtProt

NX_O95841

Human splice variants
Mouse splice variants

Protein structure