Tissue expression
Cell line expression
Protein structure
CCR8
C-C motif chemokine receptor 8CDw198, CKR-L1, CMKBR8, CMKBRL2, CY6, GPR-CY6, TER1
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. This gene is located at the chemokine receptor gene cluster region. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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GeneTex | GTX21666 | Polyclonal |
WB
EL
ICC
IHC
FC
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Novus Biologicals | NB100-709 | 2 references | Polyclonal |
WB
EL
IHC
|
|
antibodies-online | ABIN951452 | 5 references | Polyclonal |
WB
FC |
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R&D Systems | MAB1429-100 | 2 references | Monoclonal |
FC
BN |
|
Enzo Life Sciences | ALX-210-762-C200 | 5 references | Polyclonal |
WB
ICC
IHC
FC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider