Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8264 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- PRDM14 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human PRDM14.
- Description
- The PR-domain containing proteins (PRDMs) have a common involvement in the modulation of gene activities. A PR-domain family member usually produces two products, called PR-plus and PR-minus, which differ by the presence or absence of the PR domain, respectively. The PR-plus product is underexpressed or disrupted in cancer cells, whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, which is a result of either genetic or epigenetic events, appears to be a determining factor of malignancy. PRDM14 (PR domain-containing protein 14), also known as PFM11, is a 571 amino acid protein belonging to the PRDM family. Localizing to the nucleus, PRDM14 contains six C2H2-type zinc fingers and one SET domain. It is believed to participate in transcriptional regulation and may be involved in cell differentiation and tumorigenesis.
- Reactivity
- Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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