PRDM14

This gene encodes a member of the PRDI-BF1 and RIZ homology domain containing (PRDM) family of transcriptional regulators. The encoded protein may possess histone methyltransferase activity and plays a critical role in cell pluripotency by suppressing the expression of differentiation marker genes. Expression of this gene may play a role in breast cancer. [provided by RefSeq, Dec 2011]

Description

PR/SET domain 14

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Peptideatlas), Transcription factors

Chromosome

8:q13.3 (70051651 - 70071693)

Ensembl ID

ENSG00000147596  (ver. 99.38)

Orthologs

Mouse Prdm14: ENSMUSG00000042414

UniProt

Q9GZV8

neXtProt

NX_Q9GZV8

Human splice variants
Mouse splice variants