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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Flow cytometry [1]
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- Product number
- 328002 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#328002, RRID:AB_893363
- Product name
- Purified anti-human CD49e
- Antibody type
- Monoclonal
- Antigen
- U937 cells
- Description
- CD49e is a type I integral membrane glycoprotein, known as α5 integrin, VLA-5 α chain. It forms noncovalent heterodimer with integrin β1 (CD29). CD49e contains two disulfide-linked subunits of 135 kD and 24 kD, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells. CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1. It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
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Supportive validation
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- BioLegend (provider)
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- Experimental details
- Human peripheral blood lymphocytes stained with purified NKI-SAM1, followed by anti-mouse IgG FITC
- Conjugate
- Unconjugated
