Tissue expression
Cell line expression
Protein structure
ITGA5
Integrin subunit alpha 5CD49e, FNRA
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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Boster Biological Technology | ![]() |
3 references | Polyclonal |
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antibodies-online | ![]() |
5 references | Monoclonal |
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Novus Biologicals | ![]() |
Monoclonal |
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Biorbyt | ![]() |
Monoclonal |
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