Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- ABIN969221 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Integrin, alpha 5 (Fibronectin Receptor, alpha Polypeptide) (ITGA5) antibody
- Antibody type
- Monoclonal
- Description
- Ascites
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 10F6
- Vial size
- 100 μL
- Storage
- 4°C, -20°C for long term storage
Submitted references Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain.
Integrin activation by regulated dimerization and oligomerization of platelet endothelial cell adhesion molecule (PECAM)-1 from within the cell.
PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis.
Activation of alphaVbeta3 on vascular cells controls recognition of prothrombin.
Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence.
Mould AP, Askari JA, Barton S, Kline AD, McEwan PA, Craig SE, Humphries MJ
The Journal of biological chemistry 2002 May 31;277(22):19800-5
The Journal of biological chemistry 2002 May 31;277(22):19800-5
Integrin activation by regulated dimerization and oligomerization of platelet endothelial cell adhesion molecule (PECAM)-1 from within the cell.
Zhao T, Newman PJ
The Journal of cell biology 2001 Jan 8;152(1):65-73
The Journal of cell biology 2001 Jan 8;152(1):65-73
PECAM-1/CD31 trans-homophilic binding at the intercellular junctions is independent of its cytoplasmic domain; evidence for heterophilic interaction with integrin alphavbeta3 in Cis.
Wong CW, Wiedle G, Ballestrem C, Wehrle-Haller B, Etteldorf S, Bruckner M, Engelhardt B, Gisler RH, Imhof BA
Molecular biology of the cell 2000 Sep;11(9):3109-21
Molecular biology of the cell 2000 Sep;11(9):3109-21
Activation of alphaVbeta3 on vascular cells controls recognition of prothrombin.
Byzova TV, Plow EF
The Journal of cell biology 1998 Dec 28;143(7):2081-92
The Journal of cell biology 1998 Dec 28;143(7):2081-92
Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence.
Jones JI, Gockerman A, Busby WH Jr, Wright G, Clemmons DR
Proceedings of the National Academy of Sciences of the United States of America 1993 Nov 15;90(22):10553-7
Proceedings of the National Academy of Sciences of the United States of America 1993 Nov 15;90(22):10553-7
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- FACS