CABT-B12272

antibody from Creative Diagnostics

Targeting: CLEC4M CD209L, CD299, DC-SIGN2, DC-SIGNR, DCSIGNR, HP10347, LSIGN

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12272

Provider

Creative Diagnostics

Product name

Human anti-Human CLEC4M recombinant monoclonal antibody, clone SFB698 [PE]

Antibody type

Monoclonal

Description

It recognozes the human CD299 (L-SIGN) antigen, a type II integral membrane protein, also known as C-type lectin domain family 4 member M (CLEC4M) or liver/lymph node-specific ICAM-3-grabbing non-integrin. CD299 is expressed by sinusoidal endothelial cells in lymph nodes and is found in placental endothelium but not in macrophages. It is also expressed in type II alveolar cells and lung endothelial cells. CD299 has a high affinity for both intercellular adhesion molecule 3 (ICAM3) and HIV-1 gp120, and enhances HIV-1 infection of T cells. Additional information: It displays negligible binding to Fc receptors.

Reactivity

Human

Host

Human

Conjugate

Yellow dye

Isotype

IgG

Antibody clone number

SFB698

Vial size

for 100 tests

Storage

Store protected from light at 2ÿ8 °C. Do not freeze.