Tissue expression
Cell line expression
Protein structure
ELOC
Elongin CSIII, TCEB1
This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Top validated antibodies |
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Proteintech Group | 12450-1-AP | 5 references | Polyclonal |
WB
EL
ICC
IHC |
|
Invitrogen Antibodies | 12450-1-AP | Polyclonal |
WB
ICC
IHC
|
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antibodies-online | ABIN968161 | 2 references | Monoclonal |
WB
ICC
IHC
|
|
LSBio | LS-C762305 | Polyclonal |
WB
IHC |
||
NovoPro Bioscience Inc. | 115900 | Polyclonal |
WB
EL
IHC
|
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