Tissue expression
Cell line expression
Protein structure
CRYM
Crystallin muDFNA40
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. [provided by RefSeq, Sep 2014]
Top validated antibodies |
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| antibodies-online | 5 references | Monoclonal |
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| Novus Biologicals | 5 references | Monoclonal |
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| Abnova Corporation | 3 references | Monoclonal |
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| GeneTex | 1 references | Monoclonal |
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| Proteintech Group | 3 references | Polyclonal |
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