FBXO8

gene product
FBS, FBX8
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
146 antibodies from 21 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
antibodies-online
30 antibodies
Novus Biologicals
6 antibodies
OriGene
15 antibodies
Invitrogen Antibodies
4 antibodies
LifeSpan BioSciences, Inc.
36 antibodies
Atlas Antibodies
1 antibody
GeneTex
1 antibody
Abgent
1 antibody
NovoPro Bioscience Inc.
1 antibody
Biorbyt
3 antibodies
Proteintech Group
1 antibody
Abnova Corporation
5 antibodies
Aviva Systems Biology
2 antibodies
ProSci
2 antibodies
Boster Biological Technology
1 antibody
MyBioSource
3 antibodies
Creative Diagnostics
3 antibodies
Sigma-Aldrich
3 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
26 antibodies
Creative Biolabs
1 antibody