SLC8A3

This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described. [provided by RefSeq, Aug 2013]

Description

solute carrier family 8 member A3

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Predicted membrane proteins, Protein evidence (Peptideatlas), Transporters

Chromosome

14:q24.2 (70044217 - 70189070)

Ensembl ID

ENSG00000100678  (ver. 99.38)

Orthologs

Mouse Slc8a3: ENSMUSG00000079055

UniProt

P57103

neXtProt

NX_P57103

Human splice variants
Mouse splice variants