TWNK

gene product
C10orf2, FLJ21832, IOSCA, PEO, PEO1, TWINKLE, TWINL
This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2009]
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212 antibodies from 23 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
64 antibodies
Proteintech Group
2 antibodies
Bioworld Technology, Inc
1 antibody
NovoPro Bioscience Inc.
3 antibodies
Affinity Biosciences
1 antibody
LifeSpan BioSciences, Inc.
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OriGene
4 antibodies
Aviva Systems Biology
4 antibodies
GeneTex
2 antibodies
Acris Antibodies GmbH
1 antibody
Biorbyt
17 antibodies
Novus Biologicals
4 antibodies
St John's Laboratory
2 antibodies
Invitrogen Antibodies
3 antibodies
ProSci
3 antibodies
Atlas Antibodies
1 antibody
United States Biological
38 antibodies
Creative Diagnostics
5 antibodies
Creative Biolabs
4 antibodies
Boster Biological Technology
1 antibody
MyBioSource
1 antibody
Sigma-Aldrich
3 antibodies
Abnova Corporation
2 antibodies