EIF3G

This gene encodes a core subunit of the eukaryotic translation initiation factor 3 (eIF3) complex, which is required for initiation of protein translation. An N-terminal caspase cleavage product of the encoded protein may stimulate degradation of DNA. A mutation in this gene is associated with narcolepsy. [provided by RefSeq, Jul 2016]

Description

eukaryotic translation initiation factor 3 subunit G

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

19:p13.2 (10115014 - 10119918)

Ensembl ID

ENSG00000130811  (ver. 98.38)

Orthologs

Mouse Eif3g: ENSMUSG00000070319

UniProt

O75821

neXtProt

NX_O75821

Human splice variants
Mouse splice variants