Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [1]
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- Product number
- ABIN2840661 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 302-330), (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Epitope
- AA 302-330, C-Term
- Antibody clone number
- RB1937
- Vial size
- 80 μL
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Submitted references Azithromycin induces anti-viral responses in bronchial epithelial cells.
The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo.
Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression.
IFI16 in human prostate cancer.
A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L.
Cytomegalovirus induces interferon-stimulated gene expression and is attenuated by interferon in the developing brain.
Activation of anti-hepatitis C virus responses via Toll-like receptor 7.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
The nature of the catalytic domain of 2'-5'-oligoadenylate synthetases.
Enzymatic activity of 2'-5'-oligoadenylate synthetase is impaired by specific mutations that affect oligomerization of the protein.
Cloning, sequencing, and expression of two murine 2'-5'-oligoadenylate synthetases. Structure-function relationships.
Interferon-induced binding of nuclear factors to promoter elements of the 2-5A synthetase gene.
Gielen V, Johnston SL, Edwards MR
The European respiratory journal 2010 Sep;36(3):646-54
The European respiratory journal 2010 Sep;36(3):646-54
The hepatitis C virus non-structural NS5A protein impairs both the innate and adaptive hepatic immune response in vivo.
Kriegs M, Bürckstümmer T, Himmelsbach K, Bruns M, Frelin L, Ahlén G, Sällberg M, Hildt E
The Journal of biological chemistry 2009 Oct 9;284(41):28343-51
The Journal of biological chemistry 2009 Oct 9;284(41):28343-51
Therapeutic gene silencing delivered by a chemically modified small interfering RNA against mutant SOD1 slows amyotrophic lateral sclerosis progression.
Wang H, Ghosh A, Baigude H, Yang CS, Qiu L, Xia X, Zhou H, Rana TM, Xu Z
The Journal of biological chemistry 2008 Jun 6;283(23):15845-52
The Journal of biological chemistry 2008 Jun 6;283(23):15845-52
IFI16 in human prostate cancer.
Alimirah F, Chen J, Davis FJ, Choubey D
Molecular cancer research : MCR 2007 Mar;5(3):251-9
Molecular cancer research : MCR 2007 Mar;5(3):251-9
A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L.
Han JQ, Townsend HL, Jha BK, Paranjape JM, Silverman RH, Barton DJ
Journal of virology 2007 Jun;81(11):5561-72
Journal of virology 2007 Jun;81(11):5561-72
Cytomegalovirus induces interferon-stimulated gene expression and is attenuated by interferon in the developing brain.
van den Pol AN, Robek MD, Ghosh PK, Ozduman K, Bandi P, Whim MD, Wollmann G
Journal of virology 2007 Jan;81(1):332-48
Journal of virology 2007 Jan;81(1):332-48
Activation of anti-hepatitis C virus responses via Toll-like receptor 7.
Lee J, Wu CC, Lee KJ, Chuang TH, Katakura K, Liu YT, Chan M, Tawatao R, Chung M, Shen C, Cottam HB, Lai MM, Raz E, Carson DA
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 7;103(6):1828-33
Proceedings of the National Academy of Sciences of the United States of America 2006 Feb 7;103(6):1828-33
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA, Mammalian Gene Collection Program Team.
Proceedings of the National Academy of Sciences of the United States of America 2002 Dec 24;99(26):16899-903
Proceedings of the National Academy of Sciences of the United States of America 2002 Dec 24;99(26):16899-903
The nature of the catalytic domain of 2'-5'-oligoadenylate synthetases.
Sarkar SN, Ghosh A, Wang HW, Sung SS, Sen GC
The Journal of biological chemistry 1999 Sep 3;274(36):25535-42
The Journal of biological chemistry 1999 Sep 3;274(36):25535-42
Enzymatic activity of 2'-5'-oligoadenylate synthetase is impaired by specific mutations that affect oligomerization of the protein.
Ghosh A, Sarkar SN, Guo W, Bandyopadhyay S, Sen GC
The Journal of biological chemistry 1997 Dec 26;272(52):33220-6
The Journal of biological chemistry 1997 Dec 26;272(52):33220-6
Cloning, sequencing, and expression of two murine 2'-5'-oligoadenylate synthetases. Structure-function relationships.
Ghosh SK, Kusari J, Bandyopadhyay SK, Samanta H, Kumar R, Sen GC
The Journal of biological chemistry 1991 Aug 15;266(23):15293-9
The Journal of biological chemistry 1991 Aug 15;266(23):15293-9
Interferon-induced binding of nuclear factors to promoter elements of the 2-5A synthetase gene.
Rutherford MN, Hannigan GE, Williams BR
The EMBO journal 1988 Mar;7(3):751-9
The EMBO journal 1988 Mar;7(3):751-9
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Supportive validation
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC