OAS1

gene product
IFI-4, OIAS, OIASI
This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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250 antibodies from 31 providers.

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AntibodyRefsTypeAVIWBELICCIPIHCFC
Novus Biologicals
6 antibodies
Abnova Corporation
5 antibodies
antibodies-online
63 antibodies
Biorbyt
12 antibodies
Invitrogen Antibodies
4 antibodies
LifeSpan BioSciences, Inc.
53 antibodies
GeneTex
3 antibodies
Bioworld Technology, Inc
1 antibody
NovoPro Bioscience Inc.
1 antibody
Proteintech Group
1 antibody
Aviva Systems Biology
8 antibodies
OriGene
7 antibodies
Acris Antibodies GmbH
7 antibodies
Abgent
3 antibodies
Atlas Antibodies
1 antibody
St John's Laboratory
3 antibodies
Affinity Biosciences
1 antibody
Antibodies.com
1 antibody
Bioss
1 antibody
Boster Biological Technology
1 antibody
Cell Signaling Technology, Inc
1 antibody
NSJ Bioreagents
1 antibody
ProSci
4 antibodies
Creative Biolabs
5 antibodies
MyBioSource
5 antibodies
United States Biological
39 antibodies
Sigma-Aldrich
6 antibodies
RayBiotech, Inc.
2 antibodies
Abbiotec
1 antibody
Everest Biotech
1 antibody
Abbexa
3 antibodies