Antibody data
- Antibody Data
- Antigen structure
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- Product number
- abx001970 - Provider product page
- Provider
- Abbexa
- Product name
- 2'-5'-Oligoadenylate Synthetase 1 (OAS1) Antibody
- Antibody type
- Polyclonal
- Description
- OAS1 Antibody is a Rabbit Polyclonal antibody against OAS1. This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- > 1 mg/ml
- Storage
- Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
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