Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [2]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PA5-51964 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- TRIM22 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: NEVVKECQEK LQVALQRLIK EDQEAEKLED DIRQERTAWK NYIQIERQKI LKGFNEMRVI LDNEEQRELQ KLEEGEVNVL DNLAAATDQL VQQRQDASTL ISDLQRRLRG SSVEMLQDVI DVMKRSESWT LKKPKSVSKK LKSVFRV Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 54%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.3 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references Pharmacological activation of STING blocks SARS-CoV-2 infection.
Li M, Ferretti M, Ying B, Descamps H, Lee E, Dittmar M, Lee JS, Whig K, Kamalia B, Dohnalová L, Uhr G, Zarkoob H, Chen YC, Ramage H, Ferrer M, Lynch K, Schultz DC, Thaiss CA, Diamond MS, Cherry S
Science immunology 2021 May 18;6(59)
Science immunology 2021 May 18;6(59)
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of TRIM22 in Lane 1: Marker (kDa) 220, 112, 84, 47, 32, 26, 17; Lane 2: Human cell line RT-4. Samples were probed using a TRIM22 Polyclonal Antibody (Product # PA5-51964).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of TRIM22 in U-87MG ATCC cells transfected with control siRNA, target specific siRNA probe #1 and #2, using a TRIM22 Polyclonal Antibody (Product # PA5-51964). Remaining relative intensity is presented. Loading control: Anti-PPIB.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of TRIM22 in human cell line U-251 MG shows positivity in nucleus but excluded from the nucleoli. Samples were probed using a TRIM22 Polyclonal Antibody (Product # PA5-51964).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of TRIM22 in human cell line U-2 OS using a TRIM22 Polyclonal Antibody (Product # PA5-51964) shows localization to nuclear bodies.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of TRIM22 in human bone marrow using a TRIM22 Polyclonal Antibody (Product # PA5-51964) shows strong nuclear positivity in hematopoietic cells.