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- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- AMAb90535 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#AMAb90535, RRID:AB_2665578
- Product name
- Anti-ADAR
- Antibody type
- Monoclonal
- Description
- Monoclonal Antibody against Human ADAR, Clone ID: CL0176, Gene description: adenosine deaminase, RNA-specific, Alternative Gene Names: ADAR1, G1P1, IFI4, Validated applications: WB, IHC, ICC, Uniprot ID: P55265, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- CL0176
- Vial size
- 100 µl
- Concentration
- 1.0 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references The transcribed ultraconserved region uc.160+ enhances processing and A‐to‐I editing of the miR‐376 cluster: hypermethylation improves glioma prognosis
Metabolomic and Lipidomic Profiling Identifies The Role of the RNA Editing Pathway in Endometrial Carcinogenesis
Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis
Soler M, Davalos V, Sánchez‐Castillo A, Mora‐Martinez C, Setién F, Siqueira E, Castro de Moura M, Esteller M, Guil S
Molecular Oncology 2021;16(3):648-664
Molecular Oncology 2021;16(3):648-664
Metabolomic and Lipidomic Profiling Identifies The Role of the RNA Editing Pathway in Endometrial Carcinogenesis
Altadill T, Dowdy T, Gill K, Reques A, Menon S, Moiola C, Lopez-Gil C, Coll E, Matias-Guiu X, Cabrera S, Garcia A, Reventos J, Byers S, Gil-Moreno A, Cheema A, Colas E
Scientific Reports 2017;7(1)
Scientific Reports 2017;7(1)
Gene amplification-associated overexpression of the RNA editing enzyme ADAR1 enhances human lung tumorigenesis
Anadón C, Guil S, Simó-Riudalbas L, Moutinho C, Setien F, Martínez-Cardús A, Moran S, Villanueva A, Calaf M, Vidal A, Lazo P, Zondervan I, Savola S, Kohno T, Yokota J, Ribas de Pouplana L, Esteller M
Oncogene 2015;35(33):4407-4413
Oncogene 2015;35(33):4407-4413
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in U-251MG cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-ADAR antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
- Sample type
- Human
- Protocol
- Protocol
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence staining of A549 cells using the Anti-ADAR monoclonal antibody, showing specific staining in the nucleoplasm and nucleoli in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
- Sample type
- Human
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human cerebral cortex and skeletal muscle tissues using AMAb90535 antibody. Corresponding ADAR RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
