ADAR

This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]

Description

adenosine deaminase RNA specific

Protein family

Disease related genes, Enzymes, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

1:q21.3 (154582057 - 154628013)

Ensembl ID

ENSG00000160710  (ver. 99.38)

Orthologs

Mouse Adar: ENSMUSG00000027951

UniProt

P55265

neXtProt

NX_P55265

Human splice variants
Mouse splice variants