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- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 12455-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12455-1-AP, RRID:AB_2098836
- Product name
- EPS8 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EPS8 antibody (Cat. #12455-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The aging factor EPS8 induces disease-related protein aggregation through RAC signaling hyperactivation.
The 133-kDa N-terminal region of myosin XVa is critical for normal structure and function of auditory and hair cells.
EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.
miR-345 inhibits migration and stem-like cell phenotype in gastric cancer via inactivation of Rac1 by targeting EPS8.
Koyuncu S, Dominguez-Canterla Y, Alis R, Salarzai N, Petrovic D, Flames N, Vilchez D
Nature aging 2025 Sep;5(9):1750-1770
Nature aging 2025 Sep;5(9):1750-1770
The 133-kDa N-terminal region of myosin XVa is critical for normal structure and function of auditory and hair cells.
Li Y, Wang Y, Dang J, Zhuo W, Xu B, Guo Y
Acta oto-laryngologica 2025 May;145(5):363-374
Acta oto-laryngologica 2025 May;145(5):363-374
EPS8 supports pancreatic cancer growth by inhibiting BMI1 mediated proteasomal degradation of ALDH7A1.
Tan M, Meng J, Sun X, Fu X, Wang R
Experimental cell research 2021 Oct 1;407(1):112782
Experimental cell research 2021 Oct 1;407(1):112782
miR-345 inhibits migration and stem-like cell phenotype in gastric cancer via inactivation of Rac1 by targeting EPS8.
Zhang J, Wang C, Yan S, Yang Y, Zhang X, Guo W
Acta biochimica et biophysica Sinica 2020 Mar 18;52(3):259-267
Acta biochimica et biophysica Sinica 2020 Mar 18;52(3):259-267
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 12455-1-AP(EPS8 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-EPS8 (IP:12455-1-AP, 3ug; Detection:12455-1-AP 1:500) with HeLa cells lysate 3800ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EPS8 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EPS8. This antibody recognizes human,mouse,rat antigen. The EPS8 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
