Antibody data
- Antibody Data
- Antigen structure
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- Product number
- NBP2-59611F - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal MCM7 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. The specificity of this monoclonal antibody to human MCM7 was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by theMCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1 -dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Green dye
- Isotype
- IgG
- Vial size
- 100 ul
- Storage
- Store at 4C in the dark.
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