MCM7

gene product
CDC47, MCM2, PPP1R104
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
1110 antibodies from 40 providers.

Antibody properties

General

Applications

or Cancel
Antibody
Novus Biologicals
133 antibodies
Abnova Corporation
19 antibodies
Invitrogen Antibodies
5 antibodies
GeneTex
12 antibodies
OriGene
16 antibodies
antibodies-online
564 antibodies
NovoPro Bioscience Inc.
1 antibody
NSJ Bioreagents
13 antibodies
R&D Systems
8 antibodies
Atlas Antibodies
1 antibody
Proteintech Group
1 antibody
Boster Biological Technology
5 antibodies
Santa Cruz Biotechnology
1 antibody
LifeSpan BioSciences, Inc.
130 antibodies
Biorbyt
42 antibodies
Aviva Systems Biology
7 antibodies
Abgent
6 antibodies
Cell Signaling Technology, Inc
2 antibodies
Bioworld Technology, Inc
1 antibody
Signalway Antibody LLC
1 antibody
Affinity Biosciences
1 antibody
Acris Antibodies GmbH
10 antibodies
RabMAbs
7 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bethyl Laboratories
4 antibodies
Creative Diagnostics
7 antibodies
ProSci
3 antibodies
St John's Laboratory
3 antibodies
Creative Biolabs
26 antibodies
MyBioSource
5 antibodies
ABEOMICS Inc.
2 antibodies
BioLegend
2 antibodies
EMD Millipore
2 antibodies
United States Biological
40 antibodies
Sigma-Aldrich
7 antibodies
Abbiotec
1 antibody
Rockland Immunochemicals, Inc.
1 antibody
RayBiotech, Inc.
1 antibody
GenWay
4 antibodies