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Western blot
Immunocytochemistry
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [17]
- Comments [0]
- Validations
- Immunohistochemistry [2]
- Other assay [1]
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- Product number
- MA5-14288 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-MCM7 Monoclonal Antibody (47DC141 or DCS-141), Biotin
- Antibody type
- Monoclonal
- Antigen
- Recombinant full-length protein
- Description
- MA5-14291 targets CDC47 in IF, IHC (P), IP, and WB applications and shows reactivity with Canine, Human, mouse, Rat, and Xenopus laevis samples. The MA5-14291 immunogen is recombinant hCDC47 protein.
- Reactivity
- Human, Mouse, Rat, Canine, Xenopus
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- 47DC141 or DCS-141
- Vial size
- 500 µL
- Concentration
- 0.2 mg/ml
- Storage
- 4° C
Submitted references Combination therapy with carboplatin and thalidomide suppresses tumor growth and metastasis in 4T1 murine breast cancer model.
Evaluation of the effects of methotrexate released from polymeric implants in solid Ehrlich tumor.
Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage.
Synonymous codon changes in the oncogenes of the cottontail rabbit papillomavirus lead to increased oncogenicity and immunogenicity of the virus.
Cell cycle-dependent mobility of Cdc45 determined in vivo by fluorescence correlation spectroscopy.
Encapsulation of cisplatin in long-circulating and pH-sensitive liposomes improves its antitumor effect and reduces acute toxicity.
Pocket proteins suppress head and neck cancer.
Evaluation of minichromosome maintenance protein 7 as a prognostic marker in canine cutaneous mast cell tumours.
Rapamycin inhibits anal carcinogenesis in two preclinical animal models.
Metallic gold treatment reduces proliferation of inflammatory cells, increases expression of VEGF and FGF, and stimulates cell proliferation in the subventricular zone following experimental traumatic brain injury.
Persistence of high-grade cervical dysplasia and cervical cancer requires the continuous expression of the human papillomavirus type 16 E7 oncogene.
Cell proliferation index predicts relapse of brain metastases in non-irradiated patients.
Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesis.
Oxidative stress regulated expression of ubiquitin Carboxyl-terminal Hydrolase-L1: role in cell survival.
Identification, molecular cloning, and cellular distribution of the rat homolog of minichromosome maintenance protein 7 (MCM7) in the rat testis.
Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells.
Human cytomegalovirus prevents replication licensing by inhibiting MCM loading onto chromatin.
de Souza CM, Araújo e Silva AC, de Jesus Ferraciolli C, Moreira GV, Campos LC, dos Reis DC, Lopes MT, Ferreira MA, Andrade SP, Cassali GD
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 Feb;68(1):51-7
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 Feb;68(1):51-7
Evaluation of the effects of methotrexate released from polymeric implants in solid Ehrlich tumor.
de Fátima Pereira A, Mara da Costa V, Cristina Magalhães Santos M, Maciel de A Ribeiro RI, Gabriela Silva A, Carmo Horta Pinto F, Vieira Teixeira Vidigal P, Rodrigues Da Silva G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 Apr;68(3):365-8
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2014 Apr;68(3):365-8
Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage.
Broderick R, Rainey MD, Santocanale C, Nasheuer HP
The FEBS journal 2013 Oct;280(19):4888-902
The FEBS journal 2013 Oct;280(19):4888-902
Synonymous codon changes in the oncogenes of the cottontail rabbit papillomavirus lead to increased oncogenicity and immunogenicity of the virus.
Cladel NM, Budgeon LR, Hu J, Balogh KK, Christensen ND
Virology 2013 Apr 10;438(2):70-83
Virology 2013 Apr 10;438(2):70-83
Cell cycle-dependent mobility of Cdc45 determined in vivo by fluorescence correlation spectroscopy.
Broderick R, Ramadurai S, Tóth K, Togashi DM, Ryder AG, Langowski J, Nasheuer HP
PloS one 2012;7(4):e35537
PloS one 2012;7(4):e35537
Encapsulation of cisplatin in long-circulating and pH-sensitive liposomes improves its antitumor effect and reduces acute toxicity.
Leite EA, Souza CM, Carvalho-Júnior AD, Coelho LG, Lana AM, Cassali GD, Oliveira MC
International journal of nanomedicine 2012;7:5259-69
International journal of nanomedicine 2012;7:5259-69
Pocket proteins suppress head and neck cancer.
Shin MK, Pitot HC, Lambert PF
Cancer research 2012 Mar 1;72(5):1280-9
Cancer research 2012 Mar 1;72(5):1280-9
Evaluation of minichromosome maintenance protein 7 as a prognostic marker in canine cutaneous mast cell tumours.
Berlato D, Stewart J, Newton R, Maglennon GA, Monti P, Flindall A, Murphy S
Veterinary and comparative oncology 2012 Jun;10(2):135-42
Veterinary and comparative oncology 2012 Jun;10(2):135-42
Rapamycin inhibits anal carcinogenesis in two preclinical animal models.
Stelzer MK, Pitot HC, Liem A, Lee D, Kennedy GD, Lambert PF
Cancer prevention research (Philadelphia, Pa.) 2010 Dec;3(12):1542-51
Cancer prevention research (Philadelphia, Pa.) 2010 Dec;3(12):1542-51
Metallic gold treatment reduces proliferation of inflammatory cells, increases expression of VEGF and FGF, and stimulates cell proliferation in the subventricular zone following experimental traumatic brain injury.
Pedersen MØ, Larsen A, Pedersen DS, Stoltenberg M, Penkowa M
Histology and histopathology 2009 May;24(5):573-86
Histology and histopathology 2009 May;24(5):573-86
Persistence of high-grade cervical dysplasia and cervical cancer requires the continuous expression of the human papillomavirus type 16 E7 oncogene.
Jabbar SF, Abrams L, Glick A, Lambert PF
Cancer research 2009 May 15;69(10):4407-14
Cancer research 2009 May 15;69(10):4407-14
Cell proliferation index predicts relapse of brain metastases in non-irradiated patients.
Peev NA, Tonchev AB, Penkowa M, Kalevski SK, Haritonov DG, Chaldakov GN
Acta neurochirurgica 2008 Oct;150(10):1043-8; discussion 1048
Acta neurochirurgica 2008 Oct;150(10):1043-8; discussion 1048
Critical roles for non-pRb targets of human papillomavirus type 16 E7 in cervical carcinogenesis.
Balsitis S, Dick F, Dyson N, Lambert PF
Cancer research 2006 Oct 1;66(19):9393-400
Cancer research 2006 Oct 1;66(19):9393-400
Oxidative stress regulated expression of ubiquitin Carboxyl-terminal Hydrolase-L1: role in cell survival.
Shen H, Sikorska M, Leblanc J, Walker PR, Liu QY
Apoptosis : an international journal on programmed cell death 2006 Jun;11(6):1049-59
Apoptosis : an international journal on programmed cell death 2006 Jun;11(6):1049-59
Identification, molecular cloning, and cellular distribution of the rat homolog of minichromosome maintenance protein 7 (MCM7) in the rat testis.
Com E, Rolland AD, Guerrois M, Aubry F, Jégou B, Vallet-Erdtmann V, Pineau C
Molecular reproduction and development 2006 Jul;73(7):866-77
Molecular reproduction and development 2006 Jul;73(7):866-77
Repression of DNA replication licensing in quiescence is independent of geminin and may define the cell cycle state of progenitor cells.
Kingsbury SR, Loddo M, Fanshawe T, Obermann EC, Prevost AT, Stoeber K, Williams GH
Experimental cell research 2005 Sep 10;309(1):56-67
Experimental cell research 2005 Sep 10;309(1):56-67
Human cytomegalovirus prevents replication licensing by inhibiting MCM loading onto chromatin.
Wiebusch L, Uecker R, Hagemeier C
EMBO reports 2003 Jan;4(1):42-6
EMBO reports 2003 Jan;4(1):42-6
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded human tonsil stained with CDC47 antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of proliferating cells.
- Conjugate
- Biotin
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Formalin-fixed, paraffin-embedded rat breast carcinoma stained with CDC47 antibody using peroxidase-conjugate and AEC chromogen. Note nuclear staining of tumor cells.
- Conjugate
- Biotin
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunoprecipitation of CDC47 using CDC47 Monoclonal Antibody (Product # MA5-14288) on Native Human LS174T Cells.
- Conjugate
- Biotin
