Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 13874-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13874-1-AP, RRID:AB_2182638
- Product name
- S1PR5/EDG8 antibody
- Antibody type
- Polyclonal
- Description
- S1PR5/EDG8 antibody (Cat. #13874-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: FC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Sphingosine-1-Phosphate-derived 2-Hexadecenal is a central mediator of ocular neovascularization by inhibiting Sphingosine-1-Phosphate receptor 5.
Dual Mechanisms of Cognitive Function and Pathological Improvements by the Selective S1PR1/5 Modulator Siponimod in 3xTg-AD Mice.
S1PR3 inhibition impairs cell cycle checkpoint via the AKT/WEE1 pathway in oral squamous cell carcinoma.
Transcriptional signature of rapidly responding NK cells reveals S1P5 and CXCR4 as anti-tumor response disruptors.
Network Pharmacology and Experimental Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma Recurrence.
Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2.
Qian X, Ge R, Chu Y, Kuang T, Zhang X, Bennewitz K, Lou B, Hao W, Ast V, Klinke G, Poschet G, Morgenstern J, Fleming T, Hausser I, Szendroedi J, Nawroth PP, Kroll J
Nature communications 2026 Apr 14;17(1)
Nature communications 2026 Apr 14;17(1)
Dual Mechanisms of Cognitive Function and Pathological Improvements by the Selective S1PR1/5 Modulator Siponimod in 3xTg-AD Mice.
Tang C, Ding Y, Yang S, Lei X, Zhang M, Xu B, He D
Molecular neurobiology 2025 Nov 22;63(1):133
Molecular neurobiology 2025 Nov 22;63(1):133
S1PR3 inhibition impairs cell cycle checkpoint via the AKT/WEE1 pathway in oral squamous cell carcinoma.
Zhou X, Liu J, Chen X, Zhou X, Xu B, Gan G, Chen F
Journal of translational medicine 2025 May 23;23(1):573
Journal of translational medicine 2025 May 23;23(1):573
Transcriptional signature of rapidly responding NK cells reveals S1P5 and CXCR4 as anti-tumor response disruptors.
Puig-Gámez M, Van Attekum M, Theis T, Dick A, Park JE
Scientific reports 2025 Mar 28;15(1):10769
Scientific reports 2025 Mar 28;15(1):10769
Network Pharmacology and Experimental Verification to Explore the Potential Mechanism of Yin-Huo-Tang for Lung Adenocarcinoma Recurrence.
Liu D, Lin S, Li Y, Zhou T, Hu K, Li Q
Drug design, development and therapy 2022;16:375-395
Drug design, development and therapy 2022;16:375-395
Sphingosine 1-phosphate (S1P) reduces hepatocyte growth factor-induced migration of hepatocellular carcinoma cells via S1P receptor 2.
Matsushima-Nishiwaki R, Yamada N, Fukuchi K, Kozawa O
PloS one 2018;13(12):e0209050
PloS one 2018;13(12):e0209050
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The S1PR5/EDG8 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human S1PR5/EDG8. This antibody recognizes human,mouse,rat antigen. The S1PR5/EDG8 antibody has been validated for the following applications: ELISA, WB analysis.