Tissue expression
Cell line expression
Protein structure
S1PR5
Sphingosine-1-phosphate receptor 5Edg-8, EDG8
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors. [supplied by OMIM, Mar 2008]
Top validated antibodies |
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Invitrogen Antibodies | ![]() |
1 references | Polyclonal |
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LSBio | ![]() |
Polyclonal |
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Proteintech Group | ![]() |
2 references | Polyclonal |
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FineTest Biotech | ![]() |
Polyclonal |
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Biorbyt | ![]() |
Polyclonal |
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