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- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Immunocytochemistry [2]
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- Product number
- HPA019535 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA019535, RRID:AB_1848106
- Product name
- Anti-ELAC2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ELAC2, Gene description: elaC ribonuclease Z 2, Alternative Gene Names: FLJ10530, HPC2, Validated applications: WB, IHC, ICC, Uniprot ID: Q9BQ52, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Nuclear ELAC2 overexpression is associated with increased hazard for relapse after radical prostatectomy
Estrogen-Mediated Regulation of Mitochondrial Gene Expression
Schroeder C, Navid-Hill E, Meiners J, Hube-Magg C, Kluth M, Makrypidi-Fraune G, Simon R, Büscheck F, Luebke A, Goebel C, Lang D, Weidemann S, Neubauer E, Hinsch A, Jacobsen F, Lebok P, Michl U, Pehrke D, Huland H, Graefen M, Schlomm T, Sauter G, Höflmayer D
Oncotarget 2019;10(48):4973-4986
Oncotarget 2019;10(48):4973-4986
Estrogen-Mediated Regulation of Mitochondrial Gene Expression
Lopez Sanchez M, Shearwood A, Chia T, Davies S, Rackham O, Filipovska A
Molecular Endocrinology 2015;29(1):14-27
Molecular Endocrinology 2015;29(1):14-27
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Enhanced validation
Supportive validation
- Submitted by
- 55af80e3e0991
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Confocal images of immunofluorescently stained human U-2 OS cells.The protein ELAC2 is shown in green. The image to the left show cells transfected with control siRNA and the image to the right show cells where ELAC2 has been downregulated with specific siRNA.
- Sample type
- U-2 OS cells
- Primary Ab dilution
- 1:49
- Secondary Ab
- Secondary Ab
- Secondary Ab dilution
- 1:800
- Knockdown/Genetic Approaches Application
- Immunocytochemistry
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
- Sample type
- Human
