Tissue expression
Cell line expression
Protein structure
ELAC2
ElaC ribonuclease Z 2FLJ10530, HPC2
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Top validated antibodies |
|||||
Atlas Antibodies | HPA019535 | Polyclonal |
WB
ICC
IHC
|
||
Novus Biologicals | NBP1-84620 | 1 references | Polyclonal |
WB
ICC
IHC
|
|
Proteintech Group | 10071-1-AP | 12 references | Polyclonal |
WB
EL |
|
LSBio | LS-C762293 | Polyclonal |
WB
IP
IHC
|
||
FineTest Biotech | FNab02732 | Polyclonal |
WB
EL
ICC
IHC |
All Antibodies
Filters
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider