BS8728

antibody from Bioworld Technology, Inc
Targeting: ELAC2 FLJ10530, HPC2
Provider product page for BS8728
Western blot
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
BS8728 - Provider product page
Provider
Bioworld Technology, Inc
Product name
ELAC2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Zinc phosphodiesterase ELAC protein 2; ElaC homolog protein 2; Heredity prostate cancer protein 2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2; ELAC2; HPC2
Description
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Reactivity
Human
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
ELAC2 protein structure - BS8728 shown in red.